The First Thirty is an early-stage venture firm investing in AgriHealth: the deeptech and physical AI that measures, improves and verifies biological food quality — turning demand for health into an incentive for regeneration.
Decades of extractive farming have depleted essential nutrients from our soil.
Food producers struggle with unreliable supply chains while farmers face growing uncertainty due to soil degradation, energy prices and logistics disruptions.
Nutrient-depleted food contributes to trillions of annual healthcare spend on preventable conditions.
Rising consumer awareness outstrips capacity exposing the gap between what people want and what farms deliver.
New technologies are making biological quality measurable at the soil, plant and animal level. That quality can be linked to nutrition, verified and carried through the supply chain.
Once buyers can procure against biological quality, demand for health becomes an economic signal back to agriculture. This allows more value to accrue to nutrition and biological outcomes rather than only yield, uniformity and shelf life.
The wider prize is healthspan. Scaling proven health interventions could generate $12.5 trillion in additional annual global economic output by 2050, with nearly two-thirds of the opportunity coming from prevention. (McKinsey Health Institute, 2026)
We invest in the companies building the measurement, intervention, verification and data infrastructure that makes this possible. This is deeptech and physical AI applied to human longevity.
We back technologies that measure and improve nutrient density, bioavailability and biological quality at source, enabling producers to create and prove better food. Improved soil health and environments leads to nutrient-dense food which creates measurable positive health outcomes. Regenerative practices provide significant environmental and biodiversity benefits.
We back precision technologies that reduce harmful inputs and contamination, while making food safety measurable and verifiable throughout production. Precision agriculture and collaboration with nature can sharply minimize toxic farm inputs and the harm they cause. Food safety becomes measurable and verifiable in real time.
We construct our portfolio across the full value loop, investing in solutions that create and protect biological quality and in the infrastructure that makes it measurable, verifiable and economically valuable.
Each company must be capable of succeeding independently while addressing a complementary part of that loop.
Together, they connect biological quality across the food system to market demand for health, allowing proof to travel through the supply chain and economic reward to return to the source of that quality.
We are looking for innovations that:
Our companies occupy complementary layers of the AgriHealth stack, from biological intelligence and physical intervention to quality verification and market infrastructure.
