The First Thirty is an early-stage venture firm investing in AgriHealth: the deeptech and physical AI proving how the food we grow shapes how well, and how long, we live.
Decades of extractive farming have depleted essential nutrients from our soil.
Food producers struggle with unreliable supply chains while farmers face growing uncertainty due to soil degradation, energy prices and logistics disruptions.
Nutrient-depleted food contributes to trillions of annual healthcare spend on preventable conditions.
Rising consumer awareness outstrips capacity exposing the gap between what people want and what farms deliver.
Biology became measurable at the soil, plant, and animal level. That measurement can now be read and priced as a verifiable signal of nutritional quality.
The signal lets margin accrete to biological quality rather than yield and shelf life, and moves health spend from treating disease to preventing it.
The prize is healthspan: more years lived in good health, and a $12.5 trillion a year economic opportunity, most of it through prevention (McKinsey Health Institute, 2026).
We invest in the companies building that measurement and verification layer. This is deeptech and physical AI, applied to human longevity.
Improved soil health leads to nutrient-dense food which creates measurable positive health outcomes. Regenerative practices provide significant environmental and biodiversity benefits.
Precision agriculture and collaboration with nature can sharply minimize toxic farm inputs and the harm they cause. Food safety becomes measurable and verifiable in real time.
We are building a portfolio of early-stage companies that measure and optimise biological quality, raising nutrients and reducing toxins, to deliver health outcomes from soil to plate.
Together they form the infrastructure connecting farm-level measurement to consumer verification: the foundation of a new AgriHealth category.
We are looking for innovations that:
Investing in early-stage innovators turning extraction into regeneration across agriculture, health, and technology.
